Comparison of efficacy of three different venous occlusion duration on pre-treatment with injection ketamine to prevent propofol injection pain in patients undergoing surgery under general anaesthesia

Propofol is rapidly acting intravenous agent used for induction in general anaesthesia.It causes pain while administering,being uncomfortable to patients .So an observational study was done compare the effects of different time duration venous occlusion on pretreatment with injection Ketamine prevention at site. After approval ethical committee and written informed consent,ASA grade I II,60 either gender, aged between 18-60 years were assigned three groups 20 each under GA divided as GROUP K20,K40,and K60 according 20,40,and 60 seconds respectively administration ketamine(0.2mg/kg)as propofol pain.Following ketamine ,25% dose given patient asked any sensation site graded accordingly. Haemodynamics compared all groups. All reviewed haemodynamics recorded before after 5 minutes results evaluated through chi square test.P value significant (p <0.001)but not 40 seconds(p 0.201)resulting no difference score two K20 group.